Head of Medical Information (Director/Senior Director) – Medical Affairs

J oin Us in Tackling Autoimmune Disease at Its Root At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide. When you join Vor, you’re not just working on a medicine. You’re part of a mission to redefine the future of autoimmune care. Why Work at Vor? Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases. Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond. Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren’s syndrome. Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies. Location: Boston, MA preferred The Head of Medical Information (MI) will lead the function within Medical Affairs (MA). This senior leader will be responsible for building and running the MI function and preparing for the company’s first regulatory approval and commercial launch. The scope of this role will be primarily US-focused but will also have global responsibilities. As the most senior person in the function the MI lead will be accountable for leading the strategy and operations of the MI function, ensuring accurate, timely, and compliant responses to inquiries from healthcare professionals (HCPs), patients, and internal stakeholders, and be the primary point of accountability with other functions across the company (including, among others, compliance, quality, and safety & pharmacovigilance). Roles and Responsibilities: Lead the end-to-end buildout of the MI function, covering team, technology, content, SOPs, and vendor ecosystem, in alignment with the company's launch readiness timeline. Develop and execute the global MI strategy aligned with company objectives and regulatory standards. Establish MI operational infrastructure, including inbound channels, escalation pathways, response turnaround standards, and documentation requirements prior to US launch. Ensure global compliance with regulatory requirements and company policies and integration with the pharmacovigilance safety database, medical CRM, and document management system. Develop, implement, and maintain all MI governance documents, including standard operating procedures (SOPs) and/or policies and/or working instructions (WIs). Oversee development of Standard Response Documents (SRDs) library and content governance. Ensure the creation and maintenance of scientifically accurate, balanced, and up-to-date SRDs and and FAQs. Drive the implementation and optimization of emerging technologies. Lead, mentor, and develop a high-performing MI team. Foster a culture of scientific excellence, compliance rigor, and continuous improvement. Establish and maintain the MI quality assurance program. Ensure MI data management practices comply with applicable data protection regulations. Serves as the primary MI representative in cross-functional launch readiness governance. Provide regular MI performance reporting to MA leadership. Partner with cross-functional teams including Pharmacovigilance, Regulatory Affairs, Commercial, and IT to support product launches and lifecycle management. Monitor and analyze trends in medical inquiries to inform internal stakeholders (e.g., Medical Affairs, Commercial, Pharmacovigilance, Regulatory). Develop and track key performance indicators (KPIs) to monitor performance, quality, and compliance of MI services. Skills and Competencies: Deep knowledge of US regulatory framewo