opengreenhouse8vc
Senior Scientist I/II: Investigative Pathologist
Altos Labs
LocationSan Francisco Bay Area, CA, Bay Area, California
Last observed2026-06-13 05:24:10.811705
Job id8vc-altos-labs:greenhouse:6012167004
Our Mission Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com. Our Value Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission . Diversity at Altos Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment. What You Will Contribute To Altos An exciting opportunity is available for a Senior Scientist I / II to join the Institute of Medicine (IOM) Drug Discovery and Development Sciences team at Altos Labs.We are seeking a very highly motivated, creative, and collaborative individual who is passionate and dedicated to employing their scientific knowledge to help restore cell health and resilience to reverse disease. This position is ideal for candidates who have successfully completed their Residency Training Program and graduate studies and are seeking practical, hands-on experience, mentorship, and career development.The role will work closely with the Senior Director of Pathology, alongside cross-functional team members, to deliver high-quality pathology data that informs target selection, translational strategy, safety assessment, and development decisions. You will be part of a multidisciplinary team,working in a highly dynamic environment that requires effective collaboration with our early research function, Discovery Science. As a Senior Scientist, you will be expected to be an integral part of the discovery and translational project teams. Using your expertise and strong communication skills, you will guide the preclinical investigative strategy to qualify potential drug targets, help understand drug pharmacologic mechanisms, and connect the basic biology of cell and tissue injury to the pathophysiology of systemic disease. In collaboration with your cross-functional team, you will aid disease model selection and characterization, biomarker discovery, and data interpretation. A key requirement for success in this role is scientific curiosity and desire to grow and adapt to rapidly evolving technology and pipeline priorities. Responsibilities Work closely in project teams including basic science and early researchers to understand target biology paying particular attention to how molecular mechanisms could drive disease pathophysiology at the tissue and organism level Build strong trusting partnerships, working closely on the research and deep science, supporting the bridge from basic science to humans. Perform detailed histological evaluations of tissue samples to identify compound-related treatment effects, including toxicity and pharmacology Contribute to the design of in-vivo studies and provide clinical pathology and histopathological data interpretation Work with Discovery Sciences and In Vivo Translational Sciences to identify and characterize disease model systems Guide the development of novel molecular pathology assays and digital image analysis algorithms Contributes to a team culture that promotes continuous improvement, ownership, professional growth, and inclusion Contribute to the cross-functional to the creation and review of study reports Who You Are The successful candidate will have a strong pathology background of appropriate scientific training and a 3Rs-centered, welfare-oriented approach to animal-based research. Typically have 7 years + experience (including education and residency training). Be a clear and influential communicator, with the ability to give and receive feedback to improve on outcomes and impact. Have strong demonstra
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