Senior Lab Manager

Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/ , and follow us on X , LinkedIn and Facebook . Role Summary: The Senior Lab Manager works with the Lab Operations Associate Director to provide a smoothly operating laboratory for our scientific personnel. This individual needs to be willing to learn, adapt and be able to perform at a high level in a fast-paced environment. This role is based in Waltham, MA without the possibility of being a remote role. Primary Responsibilities Include: Ensure that all laboratory equipment is properly functioning; coordinate preventative maintenance, repairs, calibrations, purchase of equipment, and coordinate training as needed Manage and coordinate the maintenance agreements/service contracts for lab equipment and arranging timely maintenance visits working with lab operation associate, scientists and vendors Oversee all aspects of EHS, including tracking/managing and disposal of chemicals and hazardous/non-hazardous materials, enforcing PPE policy, assist with oversight and management of contract EHS and lab support, maintain permits, participate in and contribute to the IBC and Safety Committee Support EHS activities related to facilities (fire drills, First Aid Kits, AEDs) Serve as the Chemical Hygiene Officer May be assigned responsibilities related to secure material handling in accordance with institutional SOP's Coordinate with IT to ensure computers, data collection software and associated equipment are functioning in the lab Work with managers of new hires to coordinate training and provide safety orientation for new lab personnel and visitors to the lab. Coordinate and support incoming/outgoing domestic and international shipments as needed Monitoring of gases to support cryo freezers and equipment ELN management, coordinate training as needed, and the use of other software applications Interface with Facilities team to maintain the infrastructure serving the labs such as HVAC, exhaust systems, gases, utilities, etc. Must be willing to come in off hours to resolve lab emergencies if needed Work with functional areas to generate standing orders as needed, and maintain managed inventories of consumables and reagents Education and Skills Requirements: Bachelor’s degree in life science with 5+ years of experience in an industry BL2 wet lab; and 8 years total experience. Experience working with external vendors and service providers. Ability to effectively prioritize, shift gears, and execute tasks based on business need. Excellent decision making, communication and collaboration skills in a cross-functional and multi-level environment demonstrating very strong interpersonal skills Experience with Electronic Notebook applications, LIMS, and databases Ability to influence without authority and lead by example Ability to self-evaluate work for accuracy and completeness Experience with budget management, contract negotiation, and vendor management Operational knowledge of and troubleshooting capabilities for common lab equipment Takes initiative and exhibits independence in identifying and addressing short and long-term opportunities for optimization of lab processes Current DOT and IATA certifications preferred Must be able to lift 50 lbs. (this is the weight of one dry ice box) from the floor to approximately bench height Must be able to sit, stand, walk, bend, stretch and don appropriate PPE for prolonged pe