Supply Chain Manager, Materials Management and Planning

About Us … Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian’s programs apply our cytoDRiVE® technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian’s lead program is currently in clinical development for the treatment of patients with metastatic melanoma and non-small cell lung cancer. We’re proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options. Our Opportunity... We are looking for a highly motivated Supply Chain Manager with a strong background in supply planning, inventory management, and supplier relationship management within cGMP-regulated virtual manufacturing environments . As a key individual contributor within our Technical Operations team, you will lead material management activities in support of our clinical trials and broader CMC roadmap helping to drive the development of our first clinical stage autologous cell therapy program targeting solid tumors. In this role, you will own the planning and availability of critical raw materials, including overseeing production planning, managing safety stock targets, and coordinating external storage and material transfers. You will serve as the primary Supply Chain contact across internal teams and external partners for technical transfer and BLA readiness activities, with responsibility for material specifications, bill of materials (BOM) development, raw material risk assessments, and ensuring material readiness. You will be a vital part of a highly collaborative team working to achieve Obsidian’s vision by translating innovative science into medical breakthroughs for patients starting with our lead program OBX-115, a novel engineered tumor-infiltrating lymphocyte (TIL) therapy. This is a unique opportunity to be a contributor in a well-funded clinical company with blue chip investors, field-leading advisors, best-in-class partners, and an experienced team. You'll help us build a dynamic, innovative, passionate, collaborative, and successful organization focused on delivering transformative therapies in areas of greatest clinical need. This is a Hybrid role located in our Bedford, MA office . You Will... Core responsibilities Manage an End-to-End inventory management program through collaboration with external partners (Contract Manufacturing Organizations, External Biorepositories, Logistic Partners). Manage a detailed End-to- End MRP process including the establishment of risk-based inventory targets. Develop and manage a Sample inventory management program in partnership with Analytical Development and Quality Control groups. Support the S&OP process through End-to-End supply planning and scenario analysis Support Raw Material risk assessment and Raw Material Qualification activities as part of BLA readiness activities. Support the establishment of a supplier management program including the development of a sourcing strategy and the establishment of Supply Agreements. Contribute to the development of a formal label management program. Develop and maintain appropriate GMP controlled documents (i.e., SOPs, WIs, and Forms). Manage the sourcing of Tumor Tissue to support development activities. Coordinate various temperature controlled non-clinical shipments of raw materials between CDMOs and storage depots to support development and clinical processes. Support multiple Raw Material and TIL CDMO relationships as the supply chain representative You Bring... Core Qualifications Bachelor’s