Clinical Laboratory Scientist, (General Supervisor)

About The Role: 10x Genomics is establishing a diagnostics effort to translate our leading single-cell and spatial genomics technologies into impactful clinical applications. This Clinical Laboratory Scientist/General Supervisor position is responsible for the day-to-day execution and oversight of high complexity next-generation sequencing (NGS) testing within a CLIA-certified laboratory. This role ensures the accuracy, reliability, and timeliness of test results while maintaining full compliance with regulatory and quality standards. The General Supervisor provides technical leadership, staff supervision, and operational support to ensure efficient laboratory performance. What You Will Be Doing: Perform and oversee daily laboratory operations for high complexity NGS assays, ensuring adherence to established protocols and quality standards. Supervise and provide guidance to laboratory personnel, including training, competency assessment, and performance management. Ensure the accuracy and validity of test results through review of quality control, quality assurance, and assay performance metrics. Maintain compliance with CLIA, CAP, and other applicable regulatory requirements. Assist in the development, validation, implementation, and optimization of NGS assays and workflows. Monitor laboratory workflow, turnaround times, and resource utilization to ensure operational efficiency. Troubleshoot technical issues related to instrumentation, assays, and data analysis. Review and maintain laboratory documentation, including SOPs, validation reports, and quality records. Collaborate with laboratory leadership to support continuous quality improvement initiatives. Ensure proper maintenance and calibration of laboratory equipment. To Be Successful in the Role, You Will Need: Active California Clinical Laboratory Scientist (CLS) license (or CGMBS/generalist license) meeting CLIA requirements for high-complexity testing Bachelor’s degree in chemical, biological, physical, clinical laboratory science, or a related field Meets CLIA General Supervisor qualifications under 42 CFR 493.1461, including appropriate education, training, and experience Minimum of 2–4 years of experience in high complexity CLIA testing, with demonstrated expertise and experience in NGS technologies. Prior supervisory or leadership experience preferred. Strong knowledge of CLIA regulations and quality systems. Experience with NGS platforms, library preparation, sequencing, and bioinformatics pipelines. Additional Attributes Prior experience serving as CLIA General Supervisor Startup or high growth laboratory experience Background in medical or oncology diagnostics Excellent organizational, analytical, and problem-solving skills. Strong communication and leadership abilities. Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package. Pay Range $139,700 — $188,900 USD About 10x Genomics At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environmen