Research Assistant – Automated Organic Synthesis

Team: Laboratory Automation & Operations COMPANY SNAPSHOT We are revolutionizing organic chemistry with a fully automated synthesis platform. We combine high-throughput robotics and analytical technologies to accelerate small-molecule discovery. WHAT YOU'LL DO - Automated Synthesis Execution: Set up and run organic synthesis reactions using robotic liquid-handling systems (e.g., Opentrons OT-2), including sensitive reactions under inert conditions (glovebox, Schlenk lines) and photochemical reactions. - Robotic Work-Up Automation: Implement automated protocols for quenching, extraction, filtration, and evaporation (e.g., plate-based evaporators). - Stock Solution Preparation: Accurately weigh, dissolve, standardize, label, and organize reagent stock solutions and plates for robotic workflows. - Reagent Receipt & Qualification: Receive incoming chemical reagents and lab consumables, perform quality inspections, document batch information, and maintain inventory accuracy. - General Lab Maintenance: Manage shipping and receiving, maintain laboratory glassware and equipment, and perform routine upkeep to ensure seamless lab operations. - Data Management: Accurately document reaction parameters, analytical data (LC-MS, GC-MS), and reagent metadata in electronic lab notebooks, ensuring data integrity for AI/ML model development. - Instrument Maintenance: Regularly calibrate and maintain laboratory robotics, analytical instruments, and related equipment; troubleshoot technical issues as needed. - Protocol & Software Development: Assist in writing and refining Python or Bash scripts for automating laboratory workflows, data parsing, plate mapping, and instrument control. - Safety Compliance: Ensure adherence to chemical safety protocols, maintain accurate chemical inventories, and follow laboratory SOPs. MINIMUM QUALIFICATIONS - B.S. or M.S. in Chemistry, Chemical Engineering, or related field. - 1+ year experience in an organic chemistry laboratory (industry or academia). - Familiarity with liquid-handling robots or analytical instrumentation. - Basic scripting proficiency (Python, Bash) or demonstrated ability to quickly acquire these skills. - Strong organizational skills with meticulous attention to detail. NICE-TO-HAVE - Experience in high-throughput experimentation or automated reaction work-ups. - Knowledge of inert-atmosphere handling techniques (glovebox, Schlenk). - Experience with laboratory information management systems (LIMS) or similar data-management software. - Hands-on experience with spectroscopy and chromatography techniques. WHAT WE OFFER - An exciting opportunity to contribute directly to groundbreaking automated chemical synthesis. - Close collaboration with company founders, synthetic chemists, and machine learning experts. - Competitive salary and comprehensive benefits. - A dynamic, innovative work environment where your contributions significantly advance scientific discovery. Our company is an equal-opportunity employer.