Senior Network Systems Architect

Why Join Us? Be a hero for our rare disease patients At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them. Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work. If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team . Position Summary: We are seeking a seasoned Senior Network Systems Architect to lead the evolution of our global hybrid network and systems infrastructure. This role requires a strong foundation in Cisco Meraki, Azure Cloud networking, and Cisco ASA. The ideal candidate will bring hands-on expertise in designing, scaling, and supporting both on-premises and cloud environments, while contributing to a secure, reliable, and high-performing enterprise network. Familiarity with automation tools such as Python, Terraform, and Ansible is preferred, but not mandatory for success. Experience working with Managed Service Providers (MSPs) and global telecom carriers to negotiate contracts and provision circuits is essential. This position combines architecture with day-to-day operational support, requiring a balance of strategic planning and practical execution. ultra curious – Apply your biggest ideas in courageous ways Work Model: Flex: This role will typically require onsite work 2-3 days each week or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite. Responsibilities: Manage day to day operations, Architect, deploy, and manage hybrid infrastructure environments using Cisco Meraki, Azure networking services, and Cisco ASA firewalls Design and templatize scalable Meraki configurations and maintain consistent deployment practices across locations Create and maintain Hub-and-Spoke network architectures across Azure regions, ensuring resiliency, segmentation, and traffic control Provide a solid understanding of routing protocols, Azure routing, UDRs, NAT gateways, VPN/ExpressRoute gateways, and NVA-based architectures with multi-region failover support Develop and maintain architectural documentation including high-level designs, topology diagrams, and operational procedures Support operational excellence by serving as an escalation point for L1/L2/L3 network and systems issues and ensuring timely resolution Perform deep packet inspection and network troubleshooting using tools like Wireshark and NetFlow Participate in the planning, procurement, and provisioning of global circuits, including direct engagement and negotiation with carriers and service providers Collaborate with MSPs and internal teams to manage operations, incidents, capacity planning, and global deployments Familiar with automation tools such as Python, Terraform, and Ansible to streamline network and systems workflows Utilize tools like ThousandEyes , Azure Monitor, and log analytics to ensure observability and proactive incident response Ensure strong cross-functional collaboration wit