Vice President, Manufacturing Operations & Managing Director

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values: *RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered. *AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind. *LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives. *MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making. Summary: We are seeking an experienced and dynamic leader to join Vaxcyte as Vice President, Manufacturing Operations & Managing Director for Vaxcyte Switzerland GmbH. This role will lead a high-performing operations organization in Switzerland, supporting late-stage development, commercial readiness, and long-term growth. The role will oversee critical capital projects, scale clinical and commercial supply capabilities, and provide strategic and operational leadership across a network of Contract Manufacturing Organizations (CMOs) in Europe to ensure reliable, compliant product supply. This position is accountable for both strategic and operational leadership of GMP activities. Strategically, the role will evolve the manufacturing network, strengthen key external partnerships, and ensure alignment with corporate objectives. Operationally, it will drive site performance, scale capabilities, and deliver program milestones. The role oversees Engineering & Facilities, Manufacturing, Sourcing, and Supply Chain, with dotted-line leadership for MSAT and Quality Control in Visp. Partnering closely with Process Development, Quality Assurance, and Regulatory, this role will drive facility performance and network execution while developing a deep understanding of program drivers and translating these into actionable plans across internal teams and CMOs. This role is critical to ensure timely, compliant, and uninterrupted supply of Vaxcyte’s therapies. Strong GxP knowledge and deep expertise in biologics manufacturing, engineering, and organizational leadership are required. Essential Functions: Provide leadership, strategic direction, and risk-based oversight to translate corporate strategy into global manufacturing execution. Take strong ownership of site success. Lead and manage the Vaxcyte Switzerland organization, including direct and matrixed reporting structures. Build and develop high-performing teams across Engineering & Facilities, Manufacturing, Sourcing, Supply Chain, MSAT, and Quality Control. Oversee and strategically manage CMO relationships, including participation in Joint Steering Committees (JSCs), ensuring alignment on quality, timelines, and cost. Oversee all CMO activities and commercial supply operations to ensure reliable, compliant delivery aligned with market needs. Lead capital projects, including design, construction, startup, validation, and licensing of manufacturing facilities. Drive facility performance, site master planning, continuous improvement, COGs reduction initiatives to support scalability and long-term growth. Establish and enhance manufacturing engineering and facilities capabilities supporting clinical and commercial supply. Develop and monitor KPIs and