General Supervisor

A Rare Opportunity to Shape the Future of Genomics Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today. Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments. If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong. We are looking for a driven General Supervisor (with California Clinical Laboratory Scientist License) to support UNITY, the only non-invasive prenatal test (NIPT) that can detect inherited disorders such as sickle cell disease, spinal muscular atrophy, and cystic fibrosis in the baby directly from maternal blood. These disorders are extremely severe, but early detection and intervention can significantly improve outcomes. You will lead and oversee our growing superstar CLIA team responsible for pregnancy blood sample processing in a high complexity, high-growth CLIA setting. The General Supervisor is an onsite position and reports to the Director of Laboratory Operations. Shift Hours: Mon-Fri PM Weekday PM, 20% differential Responsibilities: Lead clinical laboratory daily supervision in alignment with company values and mission Hold General Supervisor delegation and responsibilities including oversight and support of day-to-day operations (Pre-analytical and Analytical), scheduling, and troubleshooting Manage CLIA direct reports including licensed and/or unlicensed staff (CLS, Clinical Laboratory Assistants) Oversee continuous process improvement projects including reagent quality control, tech transfer, troubleshooting, training, and validations Facilitate communication between laboratory teams and other departments or stakeholders Participate in recruiting efforts and hiring to meet sample volume demands Foster a collaborative team environment for continuous growth and building skillsets Partial owner of and leading execution of company objectives and key results Requirements: Bachelor's degree in the chemical, physical or biological sciences Current or previous supervisory experience that includes direct supervision of lab staff Minimum of 4-5 years of CLS experience in a clinical setting (molecular and/or high-complexity laboratory experience preferred) A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR, part 493) (ASCP, CGMBS or generalist license is required) Hands-on training and experience with manual molecular biology protocols, including DNA extraction, PCR, and automated liquid handlers Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems and Next-Generation Sequencing Excellent leadership, communication, and interpersonal skills Strong attention to detail and ability to work flexibly and well under given timeframes Self-starter and dynamic team player with excellent verbal and written skills Nice-To-Haves: Previous CLIA General Supervisor experience Start-up experience Knowledge of medical genetics Experience in a cell-free DNA setting Benefits And Perks: Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients Open, transparent