Wet Lab Scientist II

MyOme’s mission is to provide clinically actionable genetic information to patients throughout their lives. We combine clinical-grade whole genome sequencing, advanced AI methods for genome interpretation, and seamless digital tools for doctors and patients to order and access results. Our team is composed of seasoned entrepreneurs, scientists, and operators, and we're backed by top-tier investors. Position Overview: MyOme is seeking a Scientist II to join our research wet lab team and help drive the development, optimization, and validation of next-generation sequencing (NGS) assays. You will work closely with Clinical Operations, Bioinformatics, and Quality teams to bring new sequencing-based tests from concept through verification and validation. What You'll Do: Plan and execute structured development experiments including optimization, titrations, and bridging studies Contribute to transitioning workflows from R&D into standardized or regulated environments (e.g., CLIA/CAP-ready processes) Collaborate with the bioinformatics team to analyze results including QC metrics, run acceptance criteria, and end-to-end workflow performance to drive data-informed decisions Author and review SOPs, batch records, validation plans and validation reports Evaluate new reagents, instruments, and technologies and recommend adoption where appropriate What You'll Ne ed: M.S. with 4+ years, or B.S. with 6+ years of hands-on wet lab experience in molecular biology, genomics, biochemistry, or a related discipline. Ph.D. with 1+ years of relevant industry experience also considered. Proven, hands-on experience developing or optimizing NGS assays (e.g. whole-genome sequencing, RNASeq, etc.) end-to-end — from extraction through library prep, sequencing, and QC interpretation. Preference for R and Python experience to analyze downstream results Proficiency with sequencing platforms (e.g., Illumina, ONT, PacBio) and common library preparation chemistries. Strong working knowledge of DNA/RNA quantification and QC tools (e.g. Qubit, TapeStation/Bioanalyzer). Skilled at experimental design and troubleshooting with strong documentation habits Location, Compensation, and Benefits: Location: Onsite at our Menlo Park, CA laboratory campus. Compensation: Annual salary range is $130,000 - $160,000, based on experience. San Francisco Bay Area pay range $130,000 — $160,000 USD Benefits: Comprehensive healthcare coverage (Health, Dental, and Vision) 401K Unlimited PTO Professional development opportunities Company-sponsored off-sites and team meals during in-person meetings Direct access to company leadership and the opportunity for career growth Diversity, Inclusion, and Equal Opportunity: MyOme values diversity in all forms. We believe that diverse perspectives drive better science and better patient outcomes. We are an Equal Opportunity Employer committed to creating an inclusive workplace that empowers every individual. Why Work at MyOme? Join us if you: Want to make an impact at the intersection of healthcare and technology, changing the way people engage with their health at the genetic level Enjoy rolling up your sleeves, taking initiative, and being empowered to lead Value humility, transparency, and collaborative problem-solving Thrive in fast-moving, dynamic environments with smart, driven teammates Appreciate competitive compensation, meaningful equity, and excellent benefits Learn More: myome.com