Sr. Technical Product Manager - Data & Applied AI (Sales, Marketing, & GM)

Role Overview We are seeking a Sr. Technical Product Manager to lead the strategy and execution of data product, AI/ML system, AI-powered tooling, and automation initiatives across the go-to-market and operational teams embedded within Natera’s core business units (i.e., Oncology, Women’s Health, Organ Health), including Sales, Marketing, and Medical stakeholders. This role focuses on building, scaling, and leveraging platforms and products that power decision intelligence and activity orchestration across these domains. You will work in close collaboration with ‘S&M + GM’ leaders while building through centralized Data & AI organization platforms, standards, and governance. You will own the full product lifecycle from discovery through production, ensuring solutions are adopted, trusted, and deliver measurable business impact. In doing so, you will work hands-on as an empowered builder of AI and software solutions to improve workflow efficiency, productivity, and quality for the teams you support. This is a technical product role requiring fluency in data systems, modern data platforms, ML, and AI implementation patterns (and the ability and drive to build with them directly), combined with strong experience and stakeholder intuition across Sales, Marketing, Medical, and related functions. This role sits at the intersection of business impact and technical depth, with deep visibility into commercial performance and executive decision-making. You will have direct ownership of high-impact initiatives fueling overall organizational success. What You’ll Do Strategy & Roadmap Define and own the Data & AI product strategy and roadmap for the S&M + GM pod by deeply partnering with business leaders to proactively identify high-impact opportunities, shape problem definitions, and drive aligned priorities Translate ambiguous business problems (e.g., churn risk, campaign performance, clinical profile segmentation, next-best-action orchestration) into clear product direction and measurable outcomes Own the line between ‘what the business needs’ and ‘what gets built’ end-to-end Discovery, Experimentation, & Requirements Develop deep context on the domain so you can proactively propose solutions rather than field requests Be hands-on with data: query datasets, review schemas, and validate assumptions through analysis Lead end-to-end product discovery with interviews, workflow mapping, data assessments, ROI modeling, etc. Define clear product requirements (PRDs, user stories, acceptance criteria) and success metrics Design and run experiments to validate product performance and measure causal impact Establish leading indicators and KPIs for proactive product and process health assessments Delivery, Data, & ML Lifecycle Partner with data and AI/ML engineering resources to deliver scalable products and capabilities Guide development of robust data pipelines and unified data models (360° views across key entities) Own the end-to-end ML lifecycle: feature definition, evaluation, deployment, monitoring, drift detection, and retraining Ensure training–serving consistency, model versioning, and clear deployment decision gates Establish strong observability across data pipelines and models (data quality, latency, reliability, cost) AI Productization & Hands-On Building Define and implement AI product patterns, including agentic workflows and tool/function-calling integrations Build process automations and internal tools that improve workflow efficiency, productivity, and output quality for the teams you support Establish evaluation frameworks for LLM-powered features (faithfulness, relevance, safety, cost, latency) Implement prompt strategies, guardrails, and continuous evaluation pipelines Governance, Compliance, & Data Quality Ensure products meet regulatory and compliance requirements Champion data quality, lineage, and reliability through data contracts and observability standards Maintain strong documentation practices (e.g., model cards, data