Senior Accountant

Position Summary Natera is seeking an experienced and detail-oriented Senior Accountant to support key accounting operations related to Clinical Trials and Research & Development (R&D) activities. This role will be responsible for clinical trial accruals, prepaid expense accounting, R&D expense analysis, month-end close activities, and financial reporting processes in compliance with GAAP, ASC 730, and SOX requirements. The Senior Accountant will partner closely with Clinical Operations, FP&A, Procurement, and external vendors including CROs and clinical sites to ensure accurate accounting and reporting of clinical trial and R&D expenditures. This individual will also support process improvements and technical accounting reviews related to clinical trial agreements and research activities. This is a fully remote position, offering the opportunity to work from anywhere within the United States while collaborating with a high-performing and dynamic finance team. This is an excellent opportunity for an accounting professional looking to grow within a rapidly expanding public biotechnology company. Primary Responsibilities Clinical Trial & R&D Accounting Prepare monthly clinical trial accruals, prepaid roll-forwards, and reconciliations in accordance with ASC 730 Gather enrollment, site activity, and milestone data from Clinical Operations to support accrual calculations Review CRO and clinical site invoices against contracted milestones and fee schedules; identify and investigate variances Support R&D expense accounting, including accruals, prepaid amortization, and cost allocations Assist with technical accounting reviews of new and amended clinical trial agreements Maintain supporting schedules and documentation related to clinical trial and R&D accounting activities Partner cross-functionally with Clinical Operations, Legal, Procurement, and FP&A to ensure accurate and timely accounting treatment of research-related expenditures Financial Reporting & Month-End Close Support monthly and quarterly financial statement close processes Prepare and post month-end journal entries with appropriate supporting documentation Perform account reconciliations and detailed analyses to identify and resolve discrepancies Prepare fluctuation analyses and provide explanations for financial trends and variances Review, investigate, and correct accounting errors, inconsistencies, and reporting issues Ensure compliance with GAAP, internal controls, and company accounting policies Proactively communicate accounting, financial reporting, or control issues to management Support internal and external audit requests, including preparation of supporting documentation SOX Compliance & Process Improvement Execute SOX 404(b) controls related to clinical trial and R&D accounting processes Contribute to process improvements across clinical trial and R&D accounting workflows Participate in automation, scalability, and operational efficiency initiatives within the accounting function Collaborate with team members to improve reporting accuracy and streamline month-end close processes Revised Qualifications Bachelor’s Degree in Accounting, Finance, or related field required CPA certification preferred Minimum of 2-3 years of accounting or audit experience required Public accounting/audit background required; Big 4 experience strongly preferred Experience in biotechnology, life sciences, healthcare, or pharmaceutical industries strongly preferred Experience supporting R&D or clinical trial accounting activities preferred Equivalent combination of education and experience may be considered Revised Knowledge, Skills & Abilities Strong understanding of accrual accounting and GAAP, including ASC 730 related to R&D accounting Experience with clinical trial accounting, CRO/vendor management, or life sciences accounting processes preferred Advanced proficiency in Microsoft Excel and Microsoft Office applications Experience with Oracle ERP systems preferred Familiarity wi