Senior Director, Executive & Enterprise Communications

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior Director, Executive & Enterprise Communications will serve as a trusted communications advisor to the CEO and select senior leaders while leading enterprise internal communications across a growing global organization. This is a high-impact role for a communicator who can operate strategically and execute with excellence. Success in this position requires sound judgment, executive presence, strong writing skills, and the ability to move seamlessly between shaping a CEO keynote and building the communications infrastructure that keeps teams informed, aligned, and engaged. Reporting to the Head of Communications, this role partners closely with the Corporate Communications lead, the Associate Director of Internal Communications, and regional communications and HR partners globally. This is a rare opportunity to work directly with RevMed’s executive leadership team, shaping executive voice, internal culture, and enterprise communications at a company rapidly building toward commercial stage. Key responsibilities in this role will include: Executive Communications Serve as the primary communications partner to the CEO, leading executive messaging, speeches, talking points, and preparation for high-visibility internal and external engagements. Support senior enterprise leaders with clear, authentic, and consistent communications during key company moments. Partner with Corporate Communications on select C-suite thought leadership and external visibility initiatives. Advise senior leaders across R&D and Commercial on communications approach, leadership voice, and executive presence. Enterprise Internal Communications Lead the company’s internal communications strategy, aligned to business priorities, culture, and growth objectives. Partner with AD of Internal Comms to oversee planning and execution of major company moments, including business updates, organizational announcements, leadership forums, and employee engagement initiatives. Ensure employees receive timely, relevant communication and that leaders are equipped with tools to drive understanding and alignment across the organization. Continue to strengthen internal communications processes, channels, and operating rhythm as the company scales. Functional Business Partnership Serve as a senior communications advisor to R&D and Commercialization leaders, providing strategic counsel and hands-on support tied to business priorities. Anticipate communications risks and sensitive situations, partnering closely with Legal, HR, and senior stakeholders when needed. Global Communications Partner with regional communications and HR teams outside the U.S. to ensure messaging consistency and strong alignment globally. Establish clear ownership and standards as the company’s international footprint continues to grow. Required Skills, Experience, and Education: Core Experience 12+ years of experience in corporate, internal, executive, or related communications roles. Meaningful experience in biotech, pharma, healthcare. Proven success supporting senior executives or C-suite leaders on strategic communications. Exceptional writing, editing, and storytelling skills across internal and external audiences. Leadership & S