Senior Director, Global Commercial Development

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the VP, Global Commercial Development Disease Area Lead, this newly created role will serve as a leader for continuing to build our global oncology marketing capabilities driving global commercial strategy at product team. Candidates should be passionate about leading cross-functional collaboration and contributing as both a strategic leader and hands-on driver in a growing organization. This position is primarily remote with travel required for scientific and team meetings. Specifically, you will be responsible for: Partner across the company including with clinical development, medical affairs, market access, to drive indication strategy, shape brand strategies across the product team. Ensure global readiness to drive successful launch planning, commercialization, and performance tracking across the U.S. and key ex-U.S. markets. Execute global disease area strategy, brand strategies, including branding, positioning, messaging, and value propositions that guide regional affiliates and align with long-term portfolio goals. Lead commercial assessments and commercial development guidance for programs in early-stage development, build cross-functional relationships with early pipeline teams, and develop new ways of working for Global Commercial Development’s support of the early portfolio. Translate scientific and market insights into compelling strategies, launch narratives, and execution plans; effectively communicating recommendations and leading strategic discussions with global and regional stakeholders. Develop and refine global brand plans, including revenue and patient forecasts, to inform investment decisions, lifecycle strategies, and portfolio prioritization. Drive excellence in global launch execution: creating launch frameworks, ensuring best practices are shared across affiliates, and monitoring progress to anticipate and resolve challenges. Identify and manage external agencies, vendors, and partners to deliver impactful global campaigns, educational initiatives, and engagement platforms. Serve as a trusted resource to senior leadership in identifying opportunities to maximize commercial value, expand indications, and differentiate in competitive markets. Bring innovation and new capabilities to global marketing—collaborate with IS Commercial to integrate digital, omnichannel, and data-driven approaches to build a best-in-class commercial function. Up to 50% of travel required. Required Skills, Experience and Education: Bachelor’s degree required with at least 15 years or advanced degree with at least 8 years of progressive commercial experience in a biotechnology and/or pharmaceutical company including strategic marketing and ideally sales. Proven success of developing and executing global commercial strategy. Demonstrated ability to derive insights/analytics leading to the development of innovative commercial strategies. Strong leadership, with the ability to lead teams, work well cross-functionally, and influence across the organization to create a clear sense of direction. Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines. Strong clinical and scientific ac