ERP Systems Senior Manager (NetSuite)

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking a ERP Systems Senior Manager to serve as the primary owner and hands-on lead for NetSuite OneWorld, supporting our growing global operations and commercialization readiness. This is an individual contributor role responsible for both day-to-day system execution and longer-term ERP design and scalability. You will partner closely with Finance, FP&A, Accounting, Tax, Procurement, and IT to ensure NetSuite is accurate, compliant, scalable, and tightly aligned with business processes. This role combines deep hands-on system configuration and support with the ability to design and continuously improve ERP capabilities as the organization grows. You will play a critical role in maintaining financial integrity, supporting global entity expansion, optimizing inventory and product costing, and ensuring seamless integration across enterprise systems including Workday, Coupa, Concur, ADP, and middleware platforms. This role is pivotal in building sustainable, audit-ready ERP operations to support scale and commercialization. The ideal candidate brings strong NetSuite expertise, deep financial systems knowledge, and experience operating in a regulated life sciences environment. You thrive in a hands-on role, balancing configuration, troubleshooting, and delivery with proactive system improvements. In this role you will call upon your experience to: Serve as the primary system owner, administrator, and subject matter expert for NetSuite OneWorld. Perform hands-on configuration, troubleshooting, and optimization across NetSuite modules and business processes. Manage global subsidiaries, chart of accounts, segments, dimensions, and intercompany structures. Lead new entity setup including tax nexus, currency configuration, and reporting impacts. Configure and optimize key modules including GL, AP, AR, inventory, product costing, intercompany, and Advanced Revenue Management. Design, develop, and maintain NetSuite reports, saved searches, dashboards, and KPIs to support Finance, FP&A, and leadership. Partner with Finance and FP&A to support close, budgeting, forecasting, and reporting requirements. Administer NetSuite user access, roles, and permissions, ensuring proper segregation of duties. Support inventory valuation methodologies (standard/average costing) and variance analysis. Ensure accurate COGS flows, revenue recognition alignment, and financial reporting integrity. Support and execute system enhancements, configuration changes, and release activities with strong change management discipline. Work closely with integration teams to support and troubleshoot integrations between NetSuite and Workday, ADP, Coupa, Concur, and middleware platforms. Participate in integration design discussions and ensure NetSuite data structures and processes are aligned with upstream/downstream systems. Support SOX compliance activities including documentation, control testing, and remediation. Maintain and monitor IT General Controls (ITGCs) related to system access, change management, and data integrity. Partner with Internal Audit and external auditors to support system-related audit requests. Ensure appropriate change management controls are followed for system enhancements a