Senior Scientist I, Clinical Biomarker Development

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Senior Scientist I in Clinical Biomarker Development team, within the Translational Medicine will play a key role in the design, execution, and interpretation of clinical biomarker strategies across Revolution Medicine’s oncology pipeline. You will: Design and execute clinical biomarker strategies to support early response monitoring, patient stratification, and understanding resistance mechanisms. Support biomarker implementation for early- and late-stage oncology clinical trials. Oversee biomarker assay development, qualification, and sample analysis in collaboration with internal teams and external CROs. Analyze and interpret biomarker data in the context of clinical outcomes and present results to cross-functional teams. Contribute to clinical protocols, study reports, and regulatory documents (e.g., INDs, IBs, CSRs). Translate preclinical findings into clinically actionable biomarker hypotheses. Stay current with emerging biomarker technologies and trends in precision oncology. Required Skills, Experience and Education: PhD in a relevant scientific discipline with 3+ years of relevant industry experience in clinical biomarkers, translational medicine, or related roles. Experience supporting oncology clinical trials with biomarker components. Familiarity with biomarker platforms such as genomic/molecular and proteomic assays. Experience working with CROs and managing external vendors. Strong scientific communication skills and ability to work cross-functionally. Preferred Skills: Experience with targeted oncology therapies or RAS/MAPK pathway biology. Biological understanding of pancreatic, non small cell lung and/or colorectal cancers is preferred. Familiarity with analytical software for data anlaysis and interpretation. #LI-Hybrid #LI-SH1 The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please c