Senior Director, Organizational Development & Effectiveness

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: We are seeking a strategic and enterprise-minded leader to build and scale the Organizational Development and Effectiveness function at Revolution Medicines. As Senior Director, Organizational Effectiveness, you will define and drive the long-term strategy for leadership effectiveness, team performance and organizational health to support our rapid growth and strengthen our mission-driven, values-aligned culture. This role partners closely with HR Business Partners, Learning & Development and Senior Leaders across all functions and regions to deliver high-impact organizational programs and solutions to drive team effectiveness. You will design a scalable, data-informed approach that leverages both internal capabilities and an external network of coaches and facilitators to meet evolving business needs. This function will ensure that leaders and teams are equipped to operate effectively at scale, while providing clear insights and interventions that enhance organizational performance across the enterprise. The function will lead both functional programs as well as cross-functional matrix team programs, defining and evolving best practices for team launch, ways of working, conflict resolution and more. This position reports to the Vice President, Culture, Engagement & Learning and is based at our Redwood City headquarters. Core Responsibilities: Define and scale the Organizational Development strategy aligned to RevMed’s business priorities and core values, building a global, high-impact OD function. Lead leadership effectiveness strategy and execution. This includes, where appropriate. executive coaching and building a high-quality external coaching network. Drive team effectiveness and offsite strategy, partnering with leaders and HRBPs to enhance performance, alignment, and trust through targeted interventions and high-impact off-sites. Build and manage a scalable network of external coaches and facilitators, ensuring consistency, quality, and alignment with RevMed’s culture and standards. Strengthen talent and organizational effectiveness practices, partnering across HR to enable high-quality programs such as talent reviews, succession planning, and organizational design. Embed RevMed’s Core Values into leadership and team practices, reinforcing a collaborative, patient-focused culture across the organization. Design and deliver customized OD resources, partnering with HRBPs including workshops, leadership sessions, and tools tailored to support team launch, establishing norms, resolving conflicts and navigating stages of team development. Strategy will reflect differing needs for functional and cross-functional project teams. Leverage systems and insights to scale impact, establishing clear measures of success and continuously improving OD programs and interventions. Required Skills, Experience and Education 15+ years of progressive experience in OD, talent development, or related fields, including significant experience operating at the executive level and driving leadership effectiveness in scaling organizations. Experience in biotech, pharmaceutical, or life sciences organizations. Executive coaching certification (e.g., ICF or equivalent) with substantial ex