Senior Specialist, Clinical Supply Chain

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Independently support global clinical supply chain operations across multiple studies. This role is ideal for a detail-oriented, proactive professional who thrives in a fast-paced environment and can manage study-level supply planning, execution, and vendor coordination with minimal oversight. Independently manage clinical supply chain activities for assigned studies, including planning, execution, and reconciliation. Support global depot and site distribution, including coordination of Qualified Person (QP) release, import/export logistics, and temperature-controlled shipments. Lead clinical label design, packaging, and labeling activities in collaboration with internal teams and external vendors. Serve as the primary point of contact for CMOs, depots, and IRT vendors for assigned studies. Develop and maintain study-level supply plans and forecasts, adjusting for protocol amendments, enrollment trends, and country/site activation. Manage IRT system setup and maintenance, including drug assignment logic, inventory thresholds, and expiry management. Monitor and manage IP inventory across depots and sites, ensuring timely resupply and minimizing waste. Track and resolve temperature excursions, deviations, and other supply-related issues in collaboration with QA and vendors. Maintain study and depot-level accountability and reconciliation documentation to support regulatory compliance and study closeout. Collaborate cross-functionally with Clinical Operations, QA, Regulatory, and Project Management to ensure alignment and timely execution. Required Skills, Experience and Education: B.S. in a scientific or supply chain-related field. 3–6 years of experience in clinical supply chain and logistics, preferably in a biotech or pharmaceutical environment. Demonstrated experience supporting global clinical trials, including EU QP release and import/export logistics. Strong working knowledge of IRT systems, clinical packaging/labeling, and temperature-controlled distribution. Proficiency in Microsoft Excel. Tableau and/or PowerBI experience is a plus. Experience with oncology trials and complex study designs is a plus. Excellent organizational, communication, and problem-solving skills. Ability to work independently while collaborating effectively across functions and with external partners. Preferred Skills: Experience maintaining clinical supply plans, enrollment projections, and distribution models to support complex study designs, including cohort expansion and global site activation strategies. Excellent project management and communication skills with the ability to manage multiple concurrent studies, prioritize competing timelines, and effectively communicate supply status and risks to stakeholders and leadership teams. Skilled in managing interactive response technology (IRT/IXRS) systems, including supply strategy configuration, inventory monitoring, shipment management, and reconciliation activities. Experience overseeing external vendors, depots, and packaging organizations, including performance management, issue escalation, change control coordination, and operational governance. Experience working in a fast-paced, growth-stage biotechnology organization. #LI-Hyb