Senior Director, International FP&A

MISSION Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously. POSITION SUMMARY Reporting to the Executive Director of FP&A (based in US), the Senior Director, FP&A – International will lead and own the financial planning and analysis function for Mirum’s International Commercial Operations. Based in Zug, this role serves as the primary finance partner to International leadership, with full accountability for financial performance, planning, and strategic decision support across Europe and expanding global markets. This individual will play a critical role in building and scaling the international finance capability to support the commercialization of LIVMARLI and future pipeline assets. As a core member of the International leadership team, the role will drive financial visibility, inform strategic decisions, and ensure alignment between regional execution and global corporate objectives. This position combines strategic leadership with hands-on execution in a dynamic, growth-stage biotech environment and requires close collaboration with Commercial, Market Access, Supply Chain, R&D, Legal, Compliance, HR, and global Finance teams. JOB FUNCTIONS/RESPONSIBILITIES International Commercial Finance Leadership Own and lead FP&A for International Commercial Operations, with full accountability for regional P&L performance Serve as the primary finance partner to International leadership, influencing strategy, investment decisions, and operational execution Act as a bridge between International markets and US headquarters, ensuring alignment with global financial goals and expectations Build and evolve the international FP&A capability, including processes, tools, and team structure over time Planning, Forecasting & Performance Management Lead the annual planning process, long-range planning, and ongoing forecasting cycles for International markets Partner cross-functionally to develop robust, data-driven forecasts, challenging assumptions and identifying risks and opportunities Drive monthly and quarterly business reviews, delivering clear insights into performance drivers and actionable recommendations Ensure timely and accurate financial reporting, translating results into meaningful business insights for leadership Strategic Decision Support & Growth Lead scenario planning and financial modeling to support key business decisions, including market expansion, product launches, and resource allocation Evaluate investment opportunities through ROI analysis, supporting prioritization of high-impact initiatives Partner with Commercial and regional teams to optimize resource deployment and maximize return on investment Support launch planning for new products and geographic expansion, including financial modeling and risk assessment Pricing, Market Access & Profitability Partner with Market Access to support pricing strategy and governance, balancing access considerations with profitability objectives Conduct pricing and sensitivity analyses to inform key decisions across markets Develop a deep understanding of market dynamics, including competitive landscape, reimbursement environments, and access constraints Identify and drive margin improvement opportunities through pricing, cost optimization, and strategic trade-offs Operational Excellence & Process Improvement Drive enhancements in financial planning processes, data quality, and reporting capabilities Support the implementation and optimization of FP&A systems and tools to enable scalable growth Establish and standardize best practices across markets while accommodating local market nuances Navigate financial complexiti