Associate Director, Clinical Scientist

Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients with autoimmune diseases. Our core business strategy combines our experienced leadership team with a disciplined product candidate acquisition approach to identify, acquire and develop product candidates globally that we believe can provide superior clinical benefits to patients living with autoimmune diseases. Zenas is advancing two late-stage, potential franchise molecules, obexelimab and orelabrutinib. Obexelimab, Zenas’ lead product candidate, is a bifunctional monoclonal antibody designed to bind both CD19 and FcγRIIb, which are broadly present across B cell lineage, to inhibit the activity of cells that are implicated in many autoimmune diseases without depleting them. We believe that obexelimab’s unique mechanism of action and self-administered, subcutaneous injection regimen may broadly and effectively address the pathogenic role of B cell lineage in chronic autoimmune disease. Orelabrutinib is a potentially best-in-class, highly selective CNS-penetrant, oral, small molecule Bruton’s Tyrosine Kinase (BTK) inhibitor with the potential to address compartmentalized inflammation and disease progression in Multiple Sclerosis (MS). Zenas’ earlier stage programs include ZB021, a clinical-stage, potentially best-in-class, oral, IL-17AA/AF inhibitor; ZB022, a preclinical, potentially best-in-class, oral, brain-penetrant, TYK2 inhibitor; and ZB014, a preclinical half-life extended anti-CD-19 and FcγRIIb monoclonal antibody. We are seeking top talent who share our commitment to patients and have a track record of success in acquiring, developing and commercializing products across the globe. Our colleagues have an opportunity to engage in a fast-paced learning environment and experience individual and organizational success as we work towards becoming a global immunology and autoimmune disease leader, while living our values of Transparency, Relationships, Urgency, Excellence and Innovation – TRUE Innovation ! Position Summary: The Associate Director, Clinical Scientist is a highly collaborative, execution-focused role that supports the development, evaluation, planning and conduct of clinical studies. This position ensures the scientific integrity and accurate interpretation of study data for clinical programs within the Neurology Therapeutic Area. Reporting to the Director, Clinical Scientist, this individual serves as a key scientific and clinical partner across global clinical programs, contributing directly to the authoring of clinical study documents, supporting trial conduct, and participating in cross-functional study teams. This position works closely with Medical Directors to support medical monitoring activities, while partnering cross-functionally with Clinical Operations, Data Management, Biostatistics, Translational Sciences, Medical Affairs, and Regulatory Affairs to translate clinical strategy into operational deliverables and ensure rigorous ongoing review of trial data for quality, safety, and protocol compliance. Key Responsibilities: Actively contribute to the scientific development and execution of global clinical studies within the Neurology Therapeutic Area in alignment with the clinical development plan. Contribute to the development and/or review of clinical and scientific content for core study documents, including clinical protocols, protocol amendments, informed consent forms (ICFs), investigator brochures (IBs), and clinical study reports (CSRs). Perform ongoing, rigorous review and interpretation of emerging clinical trial data (both subject-level and aggregate safety and efficacy data) to ensure quality, completeness, consistency, and protocol compliance. Participate actively as a member of cross-functional study teams to ensure the timely and high-quality execution of clinical trial milestones. Support the Director, Clinical Scie